764191

Alkyne-PEG5-N-hydroxysuccinimidyl ester

Manufacturer: Sigma Aldrich

Synonym(S): Acetylene-PEG5-NHS ester, Alkyne-PEG5-NHS ester, Alkyne-PEG5-succinimidyl ester

Select a Size

Pack Size SKU Availability Price
10 MG 764191-10-MG In Stock ₹ 4,947.03
25 MG 764191-25-MG In Stock ₹ 10,435.30

764191 - 10 MG

₹ 4,947.03

In Stock

Quantity

1

Base Price: ₹ 4,947.03

GST (18%): ₹ 890.465

Total Price: ₹ 5,837.495

form

liquid

Quality Level

100

reaction suitability

reaction type: click chemistryreagent type: cross-linking reagent

functional group

NHS esteralkyne

storage temp.

−20°C

SMILES string

C#CCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O

InChI

1S/C18H27NO9/c1-2-6-23-8-10-25-12-14-27-15-13-26-11-9-24-7-5-18(22)28-19-16(20)3-4-17(19)21/h1H,3-15H2

InChI key

ACZDUKRWTPZVRP-UHFFFAOYSA-N

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Description

  • Application: Heterobifunctional crosslinker enabling the connection of an azide containing compound or biomolecule to one with a primary amine. The succinimidyl ester group will react preferentially with primary amines to form a covalent adduct and the terminal alkyne will react with azides via copper-catalyzed 1,3-dipolar cycloaddition click chemistry. The hydrophilic PEG spacer adds to the water solubility of this reagent, allowing for easy modification amine containing biomolecules such as antibodies, proteins and peptides with the terminal alkyne. The PEG spacer also reduces aggregation of modified proteins stored in solution by adding hydrophilic character.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Sigma Aldrich

764191

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form:
liquid

Quality Level:
100

reaction suitability:
reaction type: click chemistryreagent type: cross-linking reagent

functional group:
NHS esteralkyne

storage temp.:
−20°C

SMILES string:
C#CCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O

InChI:
1S/C18H27NO9/c1-2-6-23-8-10-25-12-14-27-15-13-26-11-9-24-7-5-18(22)28-19-16(20)3-4-17(19)21/h1H,3-15H2

InChI key:
ACZDUKRWTPZVRP-UHFFFAOYSA-N

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764205

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liquid

Quality Level:
100

reaction suitability:
reaction type: click chemistryreagent type: cross-linking reagent

functional group:
alkynemaleimide

storage temp.:
−20°C

SMILES string:
O=C(N1CCC(NCCOCCOCCOCCOCC#C)=O)C=CC1=O

InChI:
1S/C18H26N2O7/c1-2-8-24-10-12-26-14-15-27-13-11-25-9-6-19-16(21)5-7-20-17(22)3-4-18(20)23/h1,3-4H,5-15H2,(H,19,21)

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GHEBECZRHJXPTL-UHFFFAOYSA-N

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__

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O=C(NCCOCCOCCOCCOCC#C)CCCC[C@@H](SC1)[C@@]2([H])[C@]1([H])NC(N2)=O

InChI:
1S/C21H35N3O6S/c1-2-8-27-10-12-29-14-15-30-13-11-28-9-7-22-19(25)6-4-3-5-18-20-17(16-31-18)23-21(26)24-20/h1,17-18,20H,3-16H2,(H,22,25)(H2,23,24,26)/t17-,18-,20-/m1/s1

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SKMJWNZZFUDLKQ-QWFCFKBJSA-N

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__

InChI key:
__