917362
2-(4-(1-(tert-butoxycarbonyl)piperidin-4-yl)phenyl)acetic acid
≥95%
Manufacturer: Sigma Aldrich
CAS Number: 1000991-31-0
Synonym(S): Semi-flexible linker for PROTAC® development
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | 917362-100-MG | In Stock | ₹ 21,108.75 |
917362 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 21,108.75
GST (18%): ₹ 3,799.575
Total Price: ₹ 24,908.325
Quality Level
100
Assay
≥95%
form
powder
reaction suitability
reagent type: linker
mp
164-170 °C
functional group
Boccarboxylic acid
storage temp.
2-8°C
SMILES string
O=C(OC(C)(C)C)N1CCC(C2=CC=C(CC(O)=O)C=C2)CC1
Related Products
Description
- Application: 2-(4-(1-(tert-Butoxycarbonyl)piperidin-4-yl)phenyl)acetic acid is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties.
- Other Notes: Portal: Building PROTAC® Degraders for Targeted Protein DegradationCrosslinkers for BioconjugationTechnology Spotlight: Degrader Building Blocks for Targeted Protein Degradation
- Legal Information: PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Compare Similar Items
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Quality Level: 100
Assay: ≥95%
form: powder
reaction suitability: reagent type: linker
mp: 164-170 °C
functional group: Boccarboxylic acid
storage temp.: 2-8°C
SMILES string: O=C(OC(C)(C)C)N1CCC(C2=CC=C(CC(O)=O)C=C2)CC1
Quality Level:
100
Assay:
≥95%
form:
powder
reaction suitability:
reagent type: linker
mp:
164-170 °C
functional group:
Boccarboxylic acid
storage temp.:
2-8°C
SMILES string:
O=C(OC(C)(C)C)N1CCC(C2=CC=C(CC(O)=O)C=C2)CC1
Quality Level: 100
Assay: __
form: powder
reaction suitability: reagent type: linker
mp: __
functional group: amine
storage temp.: 2-8°C
SMILES string: NCC1=C(C=CC=C1)C2CCNCC2.Cl.Cl
Quality Level:
100
Assay:
__
form:
powder
reaction suitability:
reagent type: linker
mp:
__
functional group:
amine
storage temp.:
2-8°C
SMILES string:
NCC1=C(C=CC=C1)C2CCNCC2.Cl.Cl
Quality Level: 100
Assay: ≥95%
form: powder
reaction suitability: reagent type: linker
mp: __
functional group: Bochydroxyl
storage temp.: 2-8°C
SMILES string: O=C(N(CC1)CCC1C2=CC(CO)=CC=C2)OC(C)(C)C
Quality Level:
100
Assay:
≥95%
form:
powder
reaction suitability:
reagent type: linker
mp:
__
functional group:
Bochydroxyl
storage temp.:
2-8°C
SMILES string:
O=C(N(CC1)CCC1C2=CC(CO)=CC=C2)OC(C)(C)C
Quality Level: 200
Assay: ≥98.0% (T)
form: liquid
reaction suitability: __
mp: __
functional group: __
storage temp.: __
SMILES string: C[Si](C)(C)OS(=O)(=O)C(F)(F)F
Quality Level:
200
Assay:
≥98.0% (T)
form:
liquid
reaction suitability:
__
mp:
__
functional group:
__
storage temp.:
__
SMILES string:
C[Si](C)(C)OS(=O)(=O)C(F)(F)F