P3415
3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester
≥95%, powder
Manufacturer: Sigma Aldrich
CAS Number: 68181-17-9
Synonym(S): N-Succinimidyl 3-(2-pyridyldithio)propionate, SPDP
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 MG | P3415-5-MG | In Stock | ₹ 6,354.28 |
| 25 MG | P3415-25-MG | In Stock | ₹ 19,420.05 |
| 100 MG | P3415-100-MG | In Stock | ₹ 58,433.35 |
P3415 - 5 MG
In Stock
Quantity
1
Base Price: ₹ 6,354.28
GST (18%): ₹ 1,143.77
Total Price: ₹ 7,498.05
Quality Level
200
Assay
≥95%
form
powder
reaction suitability
reagent type: cross-linking reagent
mp
84-86 °C (lit.)
solubility
acetone: 50 mg/mLDMF: soluble
functional group
NHS ester
storage temp.
−20°C
SMILES string
O=C(CCSSC1=NC=CC=C1)ON2C(CCC2=O)=O
InChI
1S/C12H12N2O4S2/c15-10-4-5-11(16)14(10)18-12(17)6-8-19-20-9-3-1-2-7-13-9/h1-3,7H,4-6,8H2
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | eMolecules N-Succinimidyl 3-(2-Pyridyldithio)propionate | 68181-17-9 | MFCD00009636 | 5g | eMolecules | ₹ 13,098.38 | |
 | Chem-Impex International, Inc. 3-(2-Pyridyldithio)propionic acid N-hydroxyuccinimide ester | 68181-17-9 | MFCD00009636 | 100MG | Chem-Impex International, Inc. | ₹ 20,966.48 | |
 | Chem-Impex International, Inc. 3-(2-Pyridyldithio)propionic acid N-hydroxyuccinimide ester | 68181-17-9 | MFCD00009636 | 250MG | Chem-Impex International, Inc. | ₹ 38,549.06 | |
 | SPDP | ChemScene | ₹ 598.92 - ₹ 33,881.76 |
Related Products
Description
- General description: 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester (SPDP) is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. It is typically coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thiol-disulfide exchange buffered at pH 8.0 (7.5-8.5). Alternately, this reagent may be used as a protected thiolating reagent following initial coupling and reduction of linker. It incorporates four atom linker.[1][2]
- Application: 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester (SPDP) is useful for the preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.It has been used for antibody conjugation and as a protein cross-linker.[3][4]
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Quality Level: 200
Assay: ≥95%
form: powder
reaction suitability: reagent type: cross-linking reagent
mp: 84-86 °C (lit.)
solubility: acetone: 50 mg/mLDMF: soluble
functional group: NHS ester
storage temp.: −20°C
SMILES string: O=C(CCSSC1=NC=CC=C1)ON2C(CCC2=O)=O
InChI: 1S/C12H12N2O4S2/c15-10-4-5-11(16)14(10)18-12(17)6-8-19-20-9-3-1-2-7-13-9/h1-3,7H,4-6,8H2
Quality Level:
200
Assay:
≥95%
form:
powder
reaction suitability:
reagent type: cross-linking reagent
mp:
84-86 °C (lit.)
solubility:
acetone: 50 mg/mLDMF: soluble
functional group:
NHS ester
storage temp.:
−20°C
SMILES string:
O=C(CCSSC1=NC=CC=C1)ON2C(CCC2=O)=O
InChI:
1S/C12H12N2O4S2/c15-10-4-5-11(16)14(10)18-12(17)6-8-19-20-9-3-1-2-7-13-9/h1-3,7H,4-6,8H2
Quality Level: 200
Assay: __
form: powder
reaction suitability: __
mp: __
solubility: __
functional group: __
storage temp.: −20°C
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InChI: __
Quality Level:
200
Assay:
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form:
powder
reaction suitability:
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mp:
__
solubility:
__
functional group:
__
storage temp.:
−20°C
SMILES string:
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InChI:
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Quality Level: 200
Assay: __
form: powder
reaction suitability: __
mp: __
solubility: __
functional group: __
storage temp.: −20°C
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InChI: __
Quality Level:
200
Assay:
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form:
powder
reaction suitability:
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storage temp.:
−20°C
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Quality Level: SP2
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SP2
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