Description

• General description: Tetrapropylammonium perruthenate is a mild oxidizing agent used for the oxidation of alcohols to corresponding carbonyl compounds. It is a non-volatile, air-stable, and readily soluble reagent, which can be used either stoichiometrically or catalytically with a suitable co-oxidant.[1][2]
• Application: Tetrapropylammonium perruthenate (TPAP) can be used as a catalyst:      For the conversion of sulfides to sulfones by oxidation reaction.[2]        In the isomerization of allylic alcohols into the corresponding saturated carbonyl derivatives.[3]       Along with N-methylmorpholine N-oxide (NMO) for the cleavage of glycol to carboxylic acids.[4]TPAP can also be used as an oxidizing reagent:For the oxidation of benzyl alcohol to benzaldehyde and steroidal alcohols to corresponding ketones.[5][6]To convert N,N′-dihydroxyimidazolidines to nitronyl nitroxide free radicals.[7] To oxidize hydroxyl-substituted tri-n-butylammonium trifluoroborates to aldehydes and ketones without concomitant cleavage of the carbon-boron bond.[8][9]