Description

• General description: Boc-THP-Bpin is frequently used in metal catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Negishi couplings.[1][2]
• Application: Reagent used for Suzuki-Miyaura cross-coupling using palladium phosphine catalyst[1] Palladium-catalyzed ligand-controlled regioselective Suzuki coupling[2] Palladium-catalyzed Suzuki-Miyaura coupling[3] Suzuki coupling followed by iodolactonization reaction[4] Wrenchnolol derivative optimized for gene activation in cells[5] Reagent used in Preparation of several enzymatic inhibitors and receptor ligandsOrally active anaplastic lymphoma kinase inhibitors[6] Oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes[7] 4-arylpiperidinyl amides and N-arylpiperidin-3-yl-cyclopropanecarboxamides as novel melatonin receptor ligands[8] Quinazoline analogs as glucocerebrosidase inhibitors with chaperone activity for treatment of Gaucher disease, a lysosomal storage disorder[9] Arylpiperazine and piperidine ethers as dual acting norepinephrine reuptake inhibitors and 5-HT1A partial agonists[10]