Description

• General description: With formulation challenges in mind, we have used particle engineering technologies to develop functional excipients specifically for solid dosage forms. The products in our Parteck® portfolio feature unique particle properties tailored for excellent performance in tableting processes, for specific drug delivery technologies, or for solubility enhancement.As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
• Application: Parteck® MXP excipient is a polyvinyl alcohol-based excipient specifically designed for hot-melt extrusion to increase the solubility of poorly water soluble APIs via stabilization of the amorphous solid state. Parteck® MXP enables stable and high drug loads and can be used for a broad range of poorly water soluble APIs and a variety of final dosage forms.
• Features and Benefits: Superior supersaturation performance via precipitation inhibition High thermostability up to 250°C, extending the potential application range Stable high drug loads and suitability with a broad range of APIs Flexible release kinetics Compatible with several downstream processing capabilities, like direct compression, continuous manufacturing, thin film extrusion and 3D printing Optimized powder properties for excellent performance in the HME process Suitable polymer properties for HME, spray drying and 3D printing processes
• Legal Information: Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany