4524068

Thermo Scientific™ ProPac™ WCX-10 HPLC Columns

Separate proteins and their variants using these weak cation-exchange columns with exceptionally high resolution.

Manufacturer: Fischer Scientific

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Particle Size

10 μm

Pore Size

Nonporous

Stationary Phase

Carboxylate

Column Type

Ion Exchange

pH

2 to 12

Temperature

60°C

Product Line

ProPac

Phase

Ion Exchange

Description

  • Use Thermo Scientific™ ProPac™ WCX-10 LC Columns to provide exceptionally high resolution for separations of proteins and their variants
  • Based on stationary phases composed of 10μm nonporous polymeric beads, ProPac columns resolve isoforms that differ by a single charged residue
  • A thin, hydrophilic layer grafted to the particle core eliminates unwanted secondary interactions
  • The cation-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity
  • Multiple Formats for Greater Flexibility ProPac WCX-10 column is a weak cation-exchanger with a carboxylate functional group Column sizes range from 2mm I.D., for analytical work, up to 22mm I.D
  • for semi-prep work Superior Performance for Protein Analysis Ideal for characterization and quality control assessment of MAbs and other proteins Well-suited for characterization of related protein variants including deamidation and MAb lysine truncation variants Unequaled high-resolution separations Unmatched column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing

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