37-285-0R
Tocris Bioscience™ Indibulin
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 37-285-0R-Each-of-1 | In Stock | ₹ 93,948.40 |
37-285-0R - Each of 1
In Stock
Quantity
1
Base Price: ₹ 93,948.40
GST (18%): ₹ 16,910.712
Total Price: ₹ 1,10,859.112
Purity
>98%
Product Type
Indibulin
Inhibitors
Indibulin
Quantity
50 mg
Molecular Weight (g/mol)
389.83
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Description
- Microtubule destabilizer that blocks tubulin polymerization (IC50 = 0.3 μM)
- Blocks cell cycle progression at metaphase and displays antitumor activity against a variety of malignancies in vitro (IC50 values ranging from 0.036 - 0.285 μM)
- Induces complete tumor remission in the Yoshida AH13 rat sarcoma model in vivo
- Lacks neurotoxicity due to an ability to discriminate between posttranslationally modified tubulin in mature neuronal microtubules and less-modified tubulin present in immature neuronal or nonneuronal microtubules
- Displays oral availability and efficacy towards MDR tumor cells.
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Quantity: 50 mg
Molecular Weight (g/mol): 389.83
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