37-285-0R

Tocris Bioscience™ Indibulin

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 37-285-0R-Each-of-1 In Stock ₹ 90,317.14

37-285-0R - Each of 1

₹ 90,317.14

In Stock

Quantity

1

Base Price: ₹ 90,317.14

GST (18%): ₹ 16,257.085

Total Price: ₹ 1,06,574.225

Purity

>98%

Product Type

Indibulin

Inhibitors

Indibulin

Quantity

50 mg

Molecular Weight (g/mol)

389.83

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Description

  • Microtubule destabilizer that blocks tubulin polymerization (IC50 = 0.3 μM)
  • Blocks cell cycle progression at metaphase and displays antitumor activity against a variety of malignancies in vitro (IC50 values ranging from 0.036 - 0.285 μM)
  • Induces complete tumor remission in the Yoshida AH13 rat sarcoma model in vivo
  • Lacks neurotoxicity due to an ability to discriminate between posttranslationally modified tubulin in mature neuronal microtubules and less-modified tubulin present in immature neuronal or nonneuronal microtubules
  • Displays oral availability and efficacy towards MDR tumor cells.

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