5545831
Tocris Bioscience™ Indibulin
Microtubule destabilizer
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
Indibulin
Molecular Weight (g/mol)
389.83
Inhibitors
Indibulin
Related Products
Description
- Microtubule destabilizer that blocks tubulin polymerization (IC50 = 0.3 μM)
- Blocks cell cycle progression at metaphase and displays antitumor activity against a variety of malignancies in vitro (IC50 values ranging from 0.036 - 0.285 μM)
- Induces complete tumor remission in the Yoshida AH13 rat sarcoma model in vivo
- Lacks neurotoxicity due to an ability to discriminate between posttranslationally modified tubulin in mature neuronal microtubules and less-modified tubulin present in immature neuronal or nonneuronal microtubules
- Displays oral availability and efficacy towards MDR tumor cells.
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Purity: >98%
Product Type: Indibulin
Molecular Weight (g/mol): 389.83
Inhibitors: Indibulin
Purity:
>98%
Product Type:
Indibulin
Molecular Weight (g/mol):
389.83
Inhibitors:
Indibulin
Purity: >99%
Product Type: Indiplon
Molecular Weight (g/mol): 376.43
Inhibitors: Indiplon
Purity:
>99%
Product Type:
Indiplon
Molecular Weight (g/mol):
376.43
Inhibitors:
Indiplon
Purity: >96%
Product Type: IPA 3
Molecular Weight (g/mol): 350.45
Inhibitors: IPA 3
Purity:
>96%
Product Type:
IPA 3
Molecular Weight (g/mol):
350.45
Inhibitors:
IPA 3
Purity: >98%
Product Type: ITD 1
Molecular Weight (g/mol): 415.52
Inhibitors: ITD 1
Purity:
>98%
Product Type:
ITD 1
Molecular Weight (g/mol):
415.52
Inhibitors:
ITD 1