45-695-0
Tocris Bioscience™ PS 1145 dihydrochloride
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
PS 1145 dihydrochloride
Inhibitors
PS 1145 dihydrochloride
Quantity
50 mg
Molecular Weight (g/mol)
395.67
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Description
- Selective IκB kinase (IKK) inhibitor (IC50 = 100 nM)
- Has no effect on PKA, PKC and CKII activity
- Inhibits IκB-α phosphorylation and NFκB activation in HeLa cells
- Inhibits NFκB-mediated proinflammatory gene expression in human airway epithelial cells
- Enhances TNF-α-induced apoptosis in a multiple myeloma cell line
- Attenuates LPS-induced TNF-α production in vivo
- Orally active.
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Purity: >98%
Product Type: PS 1145 dihydrochloride
Inhibitors: PS 1145 dihydrochloride
Quantity: 50 mg
Molecular Weight (g/mol): 395.67
Purity:
>98%
Product Type:
PS 1145 dihydrochloride
Inhibitors:
PS 1145 dihydrochloride
Quantity:
50 mg
Molecular Weight (g/mol):
395.67
Purity: __
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Inhibitors: __
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Product Type: Antibody
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Molecular Weight (g/mol):
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Quantity: 1 g
Molecular Weight (g/mol): __
Purity:
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Quantity:
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Molecular Weight (g/mol):
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