5545979
Tocris Bioscience™ PS 1145 dihydrochloride
Selective IKK inhibitor; orally active
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
PS 1145 dihydrochloride
Molecular Weight (g/mol)
395.67
Inhibitors
PS 1145 dihydrochloride
Related Products
Description
- Selective IκB kinase (IKK) inhibitor (IC50 = 100 nM)
- Has no effect on PKA, PKC and CKII activity
- Inhibits IκB-α phosphorylation and NFκB activation in HeLa cells
- Inhibits NFκB-mediated proinflammatory gene expression in human airway epithelial cells
- Enhances TNF-α-induced apoptosis in a multiple myeloma cell line
- Attenuates LPS-induced TNF-α production in vivo
- Orally active.
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Purity: >98%
Product Type: PS 1145 dihydrochloride
Molecular Weight (g/mol): 395.67
Inhibitors: PS 1145 dihydrochloride
Purity:
>98%
Product Type:
PS 1145 dihydrochloride
Molecular Weight (g/mol):
395.67
Inhibitors:
PS 1145 dihydrochloride
Purity: __
Product Type: Pyridostatin pentahydrochloride
Molecular Weight (g/mol): __
Inhibitors: Pyridostatin pentahydrochloride
Purity:
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Molecular Weight (g/mol):
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Purity: 0.95
Product Type: Reversan
Molecular Weight (g/mol): 441.52
Inhibitors: Reversan
Purity:
0.95
Product Type:
Reversan
Molecular Weight (g/mol):
441.52
Inhibitors:
Reversan
Purity: __
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Molecular Weight (g/mol): __
Inhibitors: __
Purity:
__
Product Type:
__
Molecular Weight (g/mol):
__
Inhibitors:
__