51-415-0

Tocris Bioscience™ AZD 5582 dihydrochloride

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>97%

Product Type

AZD 5582 dihydrochloride

Inhibitors

AZD 5582 dihydrochloride

Quantity

50 mg

Molecular Weight (g/mol)

1088.21

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Description

  • Dimeric Smac mimetic; potent inhibitor of X-linked (XIAP) and cellular (cIAP) inhibitor of apoptosis protein (IC50 values are 15, 15 and 21 nM for XIAP, cIAP1 and cIAP2 respectively)
  • Binds to the BIR3 domain of XIAP to prevent interaction with caspase-9
  • Causes degradation of cIAP1 and cIAP2 and induces apoptosis in MDA-MB-231 breast cancer cells
  • Causes tumor regression in MDA-MB-231 xenograft-bearing mice.

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Quantity:
50 mg

Molecular Weight (g/mol):
1088.21

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