5545701
Tocris Bioscience™ AZD 5582 dihydrochloride
Dimeric Smac mimetic; potent IAP inhibitor
Manufacturer: Fischer Scientific
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Purity
>97%
Product Type
AZD 5582 dihydrochloride
Molecular Weight (g/mol)
1088.21
Inhibitors
AZD 5582 dihydrochloride
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Description
- Dimeric Smac mimetic; potent inhibitor of X-linked (XIAP) and cellular (cIAP) inhibitor of apoptosis protein (IC50 values are 15, 15 and 21 nM for XIAP, cIAP1 and cIAP2 respectively)
- Binds to the BIR3 domain of XIAP to prevent interaction with caspase-9
- Causes degradation of cIAP1 and cIAP2 and induces apoptosis in MDA-MB-231 breast cancer cells
- Causes tumor regression in MDA-MB-231 xenograft-bearing mice.
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Purity: >97%
Product Type: AZD 5582 dihydrochloride
Molecular Weight (g/mol): 1088.21
Inhibitors: AZD 5582 dihydrochloride
Purity:
>97%
Product Type:
AZD 5582 dihydrochloride
Molecular Weight (g/mol):
1088.21
Inhibitors:
AZD 5582 dihydrochloride
Purity: 98%
Product Type: BAG 956
Molecular Weight (g/mol): 427.5
Inhibitors: BAG 956
Purity:
98%
Product Type:
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Molecular Weight (g/mol):
427.5
Inhibitors:
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Purity: >98%
Product Type: BIO 5192
Molecular Weight (g/mol): 817.78
Inhibitors: BIO 5192
Purity:
>98%
Product Type:
BIO 5192
Molecular Weight (g/mol):
817.78
Inhibitors:
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Purity: >98%
Product Type: BIRT 377
Molecular Weight (g/mol): 442.13
Inhibitors: BIRT 377
Purity:
>98%
Product Type:
BIRT 377
Molecular Weight (g/mol):
442.13
Inhibitors:
BIRT 377