52-625-0

Tocris Bioscience™ PF 5274857 hydrochloride

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 52-625-0-Each-of-1 In Stock ₹ 95,577.36

52-625-0 - Each of 1

₹ 95,577.36

In Stock

Quantity

1

Base Price: ₹ 95,577.36

GST (18%): ₹ 17,203.925

Total Price: ₹ 1,12,781.285

Purity

>98%

Product Type

PF 5274857 hydrochloride

Inhibitors

PF 5274857 hydrochloride

Quantity

50 mg

Molecular Weight (g/mol)

473.42

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Description

  • High affinity and selective Smoothened (Smo) receptor antagonist (Ki = 4.6 nM)
  • Exhibits >1000-fold selectivity for Smo over a panel of other receptors, ion channels and enzymes
  • Inhibits Shh-induced Hedgehog signaling in MEF cells
  • Induces tumor regression in a medulloblastoma allograft mouse model
  • Orally available and brain penetrant.

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Purity:
>98%

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Inhibitors:
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Molecular Weight (g/mol):
473.42

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