5545638
Tocris Bioscience™ (R)-DRF053 dihydrochloride
Potent CK1 inhibitor; also inhibits cyclin-dependent kinases
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
(R)-DRF053 dihydrochloride
Molecular Weight (g/mol)
490.43
Inhibitors
(R)-DRF053 dihydrochloride
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Description
- Potent casein kinase 1 (CK1) inhibitor (IC50 = 14 nM)
- Also an ATP-competitive cyclin-dependent kinase (cdk) inhibitor (IC50 values are 0.093 - 0.29, 0.21 and 0.82 μM for cdk2, cdk5 and cdk7, respectively)
- Shown to inhibit amyloid-β production in N2A-APP695 cells.
Compare Similar Items
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Purity: >98%
Product Type: (R)-DRF053 dihydrochloride
Molecular Weight (g/mol): 490.43
Inhibitors: (R)-DRF053 dihydrochloride
Purity:
>98%
Product Type:
(R)-DRF053 dihydrochloride
Molecular Weight (g/mol):
490.43
Inhibitors:
(R)-DRF053 dihydrochloride
Purity: >99%
Product Type: (RS)-4-Carboxyphenylglycine
Molecular Weight (g/mol): 195.17
Inhibitors: (RS)-4-Carboxyphenylglycine
Purity:
>99%
Product Type:
(RS)-4-Carboxyphenylglycine
Molecular Weight (g/mol):
195.17
Inhibitors:
(RS)-4-Carboxyphenylglycine
Purity: >99%
Product Type: (RS)-MCPG disodium salt
Molecular Weight (g/mol): 253.16
Inhibitors: (RS)-MCPG disodium salt
Purity:
>99%
Product Type:
(RS)-MCPG disodium salt
Molecular Weight (g/mol):
253.16
Inhibitors:
(RS)-MCPG disodium salt
Purity: >99%
Product Type: 5-BDBD
Molecular Weight (g/mol): 355.19
Inhibitors: 5-BDBD
Purity:
>99%
Product Type:
5-BDBD
Molecular Weight (g/mol):
355.19
Inhibitors:
5-BDBD