5545741

Tocris Bioscience™ CGP 71683 hydrochloride

Highly selective and potent non-peptide NPY Y5 receptor antagonist

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>99%

Product Type

CGP 71683 hydrochloride

Molecular Weight (g/mol)

512.07

Inhibitors

CGP 71683 hydrochloride

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Description

  • Extremely selective, non-peptide NPY Y5 receptor antagonist
  • Displays > 1000-fold selectivity over Y1, Y2 and Y4 receptors; IC50 values are 1.4, 2765, 7187 and 5637 nM at cloned rat Y5, Y1, Y2 and Y4 receptors respectively
  • Potently inhibits NPY-induced food intake following i.p
  • administration in diabetic, free-feeding and fasted rats.

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