5545757

Tocris Bioscience™ CP 376395 hydrochloride

Potent and selective CRF1 antagonist; binds at an allosteric site

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>99%

Product Type

CP 376395 hydrochloride

Molecular Weight (g/mol)

362.94

Inhibitors

CP 376395 hydrochloride

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Description

  • Potent and selective CRF1 receptor antagonist (Ki values are 12 and >10000 nM for CRF1 and CRF2 receptors respectively)
  • Attenuates CRF-induced activation of the HPA axis in vivo following i.v
  • administration
  • Orally active.

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