5545872

Tocris Bioscience™ LY 2389575 hydrochloride

Selective negative allosteric modulator of mGlu3

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>98%

Product Type

LY 2389575 hydrochloride

Molecular Weight (g/mol)

438.58

Inhibitors

LY 2389575 hydrochloride

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Description

  • Selective negative allosteric modulator of mGlu3 (IC50 = 190 nM)
  • Exhibits > 65-fold selectivity for mGlu3 over other mGlu receptors
  • Abolishes the neuroprotective action of LY 379268 against amyloid β toxicity in mixed cortical neuronal and astrocyte cell cultures.

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