5545749

Tocris Bioscience™ CITCO

Selective CAR agonist

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>98%

Product Type

CITCO

Molecular Weight (g/mol)

436.74

Inhibitors

CITCO

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Description

  • Constitutive androstane receptor (CAR) agonist (EC50 = 49 nM)
  • Displays > 100-fold selectivity over PXR receptors and no activity at LXR, ERα, ERβ, PPAR, RAR, FXR, VDR and THR
  • Induces CAR nuclear translocation and expression of CYP2B6 in hepatocytes in vitro .

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