5545836
Tocris Bioscience™ ITD 1
Selective inhibitor of TGF-β signaling; induces cardiomyocyte differentiation in ESCs
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
ITD 1
Inhibitors
ITD 1
Content And Storage
-20°C
Molecular Weight (g/mol)
415.52
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Description
- Selective inhibitor of TGF-β signaling (IC50 = 0.85 μM); displays little or no inhibition of activin, Wnt or BMP signaling pathways
- Induces proteasomal degradation of the TGF-β type II receptor
- Inhibits TGF-β-induced mesoderm formation from mouse embryonic stem cells (ESCs) during early differentiation; selectively promotes the differentiation of ESCs to cardiomyocytes in vitro between days 3-5
- Does not induce differentiation of vascular smooth muscle cells or endothelial cells.
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Purity: >98%
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Inhibitors: ITD 1
Content And Storage: -20°C
Molecular Weight (g/mol): 415.52
Purity:
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Inhibitors:
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Content And Storage:
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Molecular Weight (g/mol):
415.52
Purity: >98%
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Inhibitors: J 147
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Inhibitors: JIB 04
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Molecular Weight (g/mol): 308.76
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