5545815

Tocris Bioscience™ GSK 429286

Selective Rho-kinase (ROCK) inhibitor

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>97%

Product Type

GSK 429286

Inhibitors

GSK 429286

Gene Alias

GSK429286A

Molecular Weight (g/mol)

432.37

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Description

  • Selective Rho-kinase inhibitor (IC50 values are 14, 780 and 1940 nM for ROCK1, RSK and p70S6K respectively)
  • Reverses adrenalin-induced contraction of the rat aortic ring (IC50 = 190 nM) and causes a dose-dependent decrease in mean arterial blood pressure in spontaneous hypertensive rats
  • Orally active.

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432.37

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