5545807

Tocris Bioscience™ GSK 137647

Potent and selective FFA4 (GPR120) agonist

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>99%

Product Type

GSK 137647

Molecular Weight (g/mol)

305.39

Inhibitors

GSK 137647

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Description

  • Potent and selective FFA4 (GPR120) agonist (pEC50 values are 6.3, 6.2 and 6.1 at the human, mouse and rat receptor, respectively)
  • Exhibits ≥100-fold selectivity against a panel of 61 targets including FFA1, FFA2 and FFA3
  • Enhances glucose-stimulated insulin secretion in MIN6 cells
  • Induces intracellular calcium accumulation in U2OS cells; this activity is inhibited by AH 7614 (Cat
  • No
  • 5256).

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