508110R

Tocris Bioscience™ J 147

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 508110R-Each-of-1 In Stock ₹ 22,529.66

508110R - Each of 1

₹ 22,529.66

In Stock

Quantity

1

Base Price: ₹ 22,529.66

GST (18%): ₹ 4,055.339

Total Price: ₹ 26,584.999

Purity

>99%

Product Type

J 147

Inhibitors

J 147

Quantity

10 mg

Molecular Weight (g/mol)

350.33

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Description

  • Potent neuroprotective and neurotrophic compound
  • Protects against neurotoxicity in cortical neurons in vitro (EC50 = 25 - 200 nM)
  • Reduces soluble Aβ40 and Aβ42 levels and increases BDNF levels in the hippocampus in vivo
  • Enhances memory in wild type rats
  • Prevents memory deficits and rescues cognitive deficits in young and aged transgenic Alzheimer's disease mice, respectively
  • Orally active.

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