46-515-0R
Tocris Bioscience™ JW 67
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 46-515-0R-Each-of-1 | In Stock | ₹ 90,424.00 |
46-515-0R - Each of 1
In Stock
Quantity
1
Base Price: ₹ 90,424.00
GST (18%): ₹ 16,276.32
Total Price: ₹ 1,06,700.32
Purity
>97%
Product Type
JW 67
Inhibitors
JW 67
Quantity
50 mg
Molecular Weight (g/mol)
394.38
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Description
- Inhibitor of canonical Wnt pathway signaling (IC50 = 1.17 μM); targets the β-catenin destruction complex (GSK-3β/AXIN/APC) to induce β-catenin degradation
- Selective for the canonical Wnt pathway over the Sonic hedgehog (Shh) and NF-κB pathways
- Blocks G1/S cell cycle progression in colorectal cancer (CRC) cell lines (GI50 = 7.8 μM).
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