5545841
Tocris Bioscience™ JW 67
Wnt pathway inhibitor; induces degradation of active β-catenin
Manufacturer: Fischer Scientific
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Purity
>97%
Product Type
JW 67
Molecular Weight (g/mol)
394.38
Inhibitors
JW 67
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Description
- Inhibitor of canonical Wnt pathway signaling (IC50 = 1.17 μM); targets the β-catenin destruction complex (GSK-3β/AXIN/APC) to induce β-catenin degradation
- Selective for the canonical Wnt pathway over the Sonic hedgehog (Shh) and NF-κB pathways
- Blocks G1/S cell cycle progression in colorectal cancer (CRC) cell lines (GI50 = 7.8 μM).
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Purity: >97%
Product Type: JW 67
Molecular Weight (g/mol): 394.38
Inhibitors: JW 67
Purity:
>97%
Product Type:
JW 67
Molecular Weight (g/mol):
394.38
Inhibitors:
JW 67
Purity: >99%
Product Type: K 02288
Molecular Weight (g/mol): 352.38
Inhibitors: K 02288
Purity:
>99%
Product Type:
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Molecular Weight (g/mol):
352.38
Inhibitors:
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Purity: >98%
Product Type: KHS 101 hydrochloride
Molecular Weight (g/mol): 375.92
Inhibitors: KHS 101 hydrochloride
Purity:
>98%
Product Type:
KHS 101 hydrochloride
Molecular Weight (g/mol):
375.92
Inhibitors:
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Purity: >99%
Product Type: KRCA 0008
Molecular Weight (g/mol): 609.12
Inhibitors: KRCA 0008
Purity:
>99%
Product Type:
KRCA 0008
Molecular Weight (g/mol):
609.12
Inhibitors:
KRCA 0008