5545838

Tocris Bioscience™ J 147

Neuroprotective and neurotrophic compound; reduces Aβ40 and Aβ42 levels

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>99%

Product Type

J 147

Molecular Weight (g/mol)

350.33

Inhibitors

J 147

Related Products

Img

Fischer Scientific

508110R

--

Img

Fischer Scientific

508150R

--

Img

Fischer Scientific

5545807

Potent and selective FFA4 (GPR120) ...

Img

Fischer Scientific

5545834

Group I PAK inhibitor...

Img

Fischer Scientific

52-575-0

--

Img

Fischer Scientific

52-545-0

--

Img

Fischer Scientific

42-135-0

--

Img

Fischer Scientific

36-425-0R

--

Description

  • Potent neuroprotective and neurotrophic compound
  • Protects against neurotoxicity in cortical neurons in vitro (EC50 = 25 - 200 nM)
  • Reduces soluble Aβ40 and Aβ42 levels and increases BDNF levels in the hippocampus in vivo
  • Enhances memory in wild type rats
  • Prevents memory deficits and rescues cognitive deficits in young and aged transgenic Alzheimer's disease mice, respectively
  • Orally active.

Compare Similar Items

Show Difference

Img

Fischer Scientific

5545838

Neuroprotective and neurotrophic co...


Purity:
>99%

Product Type:
J 147

Molecular Weight (g/mol):
350.33

Inhibitors:
J 147

Img

Fischer Scientific

5545839

Pan Jumonji inhibitor; active in vi...


Purity:
>99%

Product Type:
JIB 04

Molecular Weight (g/mol):
308.76

Inhibitors:
JIB 04

Img

Fischer Scientific

5545841

Wnt pathway inhibitor; induces degr...


Purity:
>97%

Product Type:
JW 67

Molecular Weight (g/mol):
394.38

Inhibitors:
JW 67

Img

Fischer Scientific

5545842

Type 1 BMP receptor inhibitor...


Purity:
>99%

Product Type:
K 02288

Molecular Weight (g/mol):
352.38

Inhibitors:
K 02288