5545886

Tocris Bioscience™ ML 00253764 hydrochloride

Melanocortin MC4 receptor antagonist; brain penetrant

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Purity

>98%

Product Type

ML 00253764 hydrochloride

Molecular Weight (g/mol)

413.71

Inhibitors

ML 00253764 hydrochloride

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Description

  • Non-peptide, melanocortin MC4 receptor antagonist (IC50 values are 320, 810 and 2120 nM for MC4, MC3 and MC5 receptors respectively)
  • Decreases cAMP accumulation in HEK-293 cells expressing the MC4 receptor
  • Increases food intake and reduces loss of lean body mass in tumor bearing mice
  • Brain penetrant.

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