Positive allosteric modulator of α4β2 receptor; increases the potency of Ach-evoked currents ∽60 fold without effecting the maximum efficacy (HEK293-hα4β2 cells)
Reduces the rate of recovery from desensitization and slows the rate of deactivation
Displays a synergistic effect on the Emax when given with NS206 at 3α:2β receptors.