5545962
Tocris Bioscience™ PHT 427
Dual Akt and PDK1 inhibitor; antitumor
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
PHT 427
Molecular Weight (g/mol)
409.61
Inhibitors
PHT 427
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Description
- Dual Akt and PDK1 inhibitor; binds the pleckstrin homology (PH) domain of Akt and PDK1 (Ki values are 2.7 and 5.2 μM, respectively)
- Inhibits Akt phosphorylation and Akt downstream targets; also induces apoptosis in vitro
- Displays synergistic antitumor effect when combined with chemotherapeutics in breast cancer mouse models.
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Purity: >98%
Product Type: PHT 427
Molecular Weight (g/mol): 409.61
Inhibitors: PHT 427
Purity:
>98%
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PHT 427
Molecular Weight (g/mol):
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Inhibitors:
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Purity: >98%
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Molecular Weight (g/mol): 438.48
Inhibitors: PPQ 102
Purity:
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Product Type:
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Molecular Weight (g/mol):
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Molecular Weight (g/mol): 235.24
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Purity:
>99%
Product Type:
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Molecular Weight (g/mol):
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Purity: >98%
Product Type: PS 1145 dihydrochloride
Molecular Weight (g/mol): 395.67
Inhibitors: PS 1145 dihydrochloride
Purity:
>98%
Product Type:
PS 1145 dihydrochloride
Molecular Weight (g/mol):
395.67
Inhibitors:
PS 1145 dihydrochloride