Thermo Scientific™ PathoDx™ Herpes Typing Kit

Description

• Perform an immunofluorescent test for detection and typing of herpes simplex virus I and II in direct clinical specimens and tissue cultures using Thermo Scientific™ Remel™ PathoDx™ Herpes Typing Kit
• Herpes simplex virus (HSV) is an ancient and ubiquitous virus, known to cause acute and recurrent infections in humans
• In the 1960s, it was recognized that HSV consisted of two distinct types, HSV-I and HSV-II 1
• HSV-I was considered to be primarily associated with ocular and oral infection (above the waist) while HSV-II was considered to be a genital infection (below the waist)
• PathoDx Herpes Typing Kit uses four fluorescein-labeled monoclonal antibodies specific for HSV-I and HSV-II (two for HSV-I; two for HSV-II) to detect and identify Herpes Simplex Virus
• The standard method for diagnosis of HSV is its growth in tissue culture cells 2,3
• The reagents are specific for each HSV type and will not show any cross-reactive staining
• Ready-to-use – Prepared reagents Easy-to-store – Store at 2-8°C Easy to interpret – HSV-I Typing Reagent will show a diffuse bright apple-green fluorescence throughout, whereas HSV-II Typing Reagent will show a speckled distribution (granular pattern) of intense fluorescent staining in the cytoplasm and nucleus HSV-I Typing Reagent (Purple cap) is one plastic dropper bottle containing 5.0 mL of fluorescein-labeled purified murine monoclonal antibodies specific for HSV-I, Evans Blue counterstain, an inhibitor of nonspecific staining, and 0.098% sodium azide in a protein-stabilized buffer solution
• HSV-II Typing Reagent (Pink cap) is one plastic dropper bottle containing 5.0 mL of fluorescein-labeled purified murine monoclonal antibodies specific for HSV-II, Evans Blue counterstain, an inhibitor of nonspecific staining, and 0.098% sodium azide in a protein-stabilized buffer solution
• The PathoDx Herpes Typing Kit contents the following reagents: HSV-I Typing Reagent – 1 dropper bottle (purple cap) HSV-II Typing Reagent – 1 dropper bottle (pink cap) Mounting Fluid (R62230) – 1 dropper bottle (black cap) Herpes Typing Control Slides (R62251) – 1 pack of 5 Not all products are available for sale in all territories
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• Remel™ and Oxoid™ products are now part of the Thermo Scientific brand.