52-405-0

Tocris Bioscience™ TC-S 7006

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 52-405-0-Each-of-1 In Stock ₹ 1,42,286.28

52-405-0 - Each of 1

₹ 1,42,286.28

In Stock

Quantity

1

Base Price: ₹ 1,42,286.28

GST (18%): ₹ 25,611.53

Total Price: ₹ 1,67,897.81

Purity

>99%

Product Type

TC-S 7006

Inhibitors

TC-S 7006

Quantity

50 mg

Molecular Weight (g/mol)

404.83

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Description

  • Potent and selective Tpl2 (Cot; MAP3K8) inhibitor (IC50 = 50 nM)
  • Selective for Tpl2 over MEK, p38, Src, MK2, PKC and EGFR
  • Inhibits LPS-induced TNF-α secretion from monocytes and attenuates acute myeloid leukemia (AML) cell proliferation in vitro
  • Also reduces cytolytic activity of human CD8+ cytotoxic T lymphocytes
  • Cell permeable.

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