52-885-0

Tocris Bioscience™ R 268712

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 52-885-0-Each-of-1 In Stock ₹ 1,39,633.92

52-885-0 - Each of 1

₹ 1,39,633.92

In Stock

Quantity

1

Base Price: ₹ 1,39,633.92

GST (18%): ₹ 25,134.106

Total Price: ₹ 1,64,768.026

Purity

>98%

Product Type

R 268712

Inhibitors

R 268712

Quantity

50 mg

Molecular Weight (g/mol)

363.39

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Description

  • Potent and selective inhibitor of the TGF-β type I receptor/ALK5 (IC50 = 2.5 nM)
  • Exhibits ∽5000-fold selectivity over p38 MAPK
  • Suppresses development of renal fibrosis in a unilateral ureteral obstruction model
  • Also reduces proteinuria, glomerulosclerosis and improves renal function in an anti-Thy1 glomerulonephritis model
  • Orally bioavailable.

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