53-185-0

Tocris Bioscience™ AEE 788

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 53-185-0-Each-of-1 In Stock ₹ 1,31,505.72

53-185-0 - Each of 1

₹ 1,31,505.72

In Stock

Quantity

1

Base Price: ₹ 1,31,505.72

GST (18%): ₹ 23,671.03

Total Price: ₹ 1,55,176.75

Purity

>98%

Product Type

AEE 788

Inhibitors

AEE 788

Quantity

50 mg

Molecular Weight (g/mol)

440.58

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Description

  • Potent EGFR and VEGFR inhibitor (IC50 values are 2, 6, 59, 77, 160 and 330 nM for EGFR, ErbB2, VEGFR-1, VEGFR-2, ErbB4 and VEGFR-3 respectively)
  • Also inhibits c-Abl, c-Fms and c-Src (IC50 values are 52, 60 and 61 nM respectively)
  • Inhibits proliferation of EGFR and ErbB2 overexpressing cancer cell lines in vitro
  • Inhibits tumor xenograft growth and VEGF-induced angiogenesis in mice
  • Orally active.

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