5546131
Tocris Bioscience™ AEE 788
Potent EGFR and VEGFR inhibitor
Manufacturer: Fischer Scientific
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Purity
>98%
Product Type
AEE 788
Molecular Weight (g/mol)
440.58
Inhibitors
AEE 788
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Description
- Potent EGFR and VEGFR inhibitor (IC50 values are 2, 6, 59, 77, 160 and 330 nM for EGFR, ErbB2, VEGFR-1, VEGFR-2, ErbB4 and VEGFR-3 respectively)
- Also inhibits c-Abl, c-Fms and c-Src (IC50 values are 52, 60 and 61 nM respectively)
- Inhibits proliferation of EGFR and ErbB2 overexpressing cancer cell lines in vitro
- Inhibits tumor xenograft growth and VEGF-induced angiogenesis in mice
- Orally active.
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Purity: >98%
Product Type: AEE 788
Molecular Weight (g/mol): 440.58
Inhibitors: AEE 788
Purity:
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Molecular Weight (g/mol):
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Inhibitors:
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Molecular Weight (g/mol): 454.75
Inhibitors: Rho GTPase Inhibitors
Purity:
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Molecular Weight (g/mol):
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Inhibitors:
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Purity: >98%
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Molecular Weight (g/mol): 351.01
Inhibitors: EPAC Inhibitors
Purity:
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Product Type:
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Molecular Weight (g/mol):
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Inhibitors:
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Purity: >99%
Product Type: CKI 7 dihydrochloride
Molecular Weight (g/mol): 358.67
Inhibitors: CKI 7 dihydrochloride
Purity:
>99%
Product Type:
CKI 7 dihydrochloride
Molecular Weight (g/mol):
358.67
Inhibitors:
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