926248

Redox Responsive Poly(ethylene glycol)-block-poly(lactide-alt-glycolide)

PEG average Mn 5000, PLGA Mn 15000

Manufacturer: Sigma Aldrich

Synonym(S): Drug release, PEG-PLGA with disulfide linkage, PEG-SS-PLGA, Stimuli-responsive

Select a Size

Pack Size SKU Availability Price
1 G 926248-1-G In Stock ₹ 65,360.00

926248 - 1 G

₹ 65,360.00

In Stock

Quantity

1

Base Price: ₹ 65,360.00

GST (18%): ₹ 11,764.80

Total Price: ₹ 77,124.80

form

powder, chunks or granules

Quality Level

100

mol wt

PEG average Mn 5000PLGA Mn 15000

storage temp.

2-8°C

SMILES string

O=C(C(C)OC(CO[H])=O)OCCSSCCOC(OCCOCCOC)=O

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Description

  • Application: PEG-SS-PLGA is a redox responsive, biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic poly(lactide-alternative-glycolide) (PLGA) block, with a reducible disulfide linkage between blocks. This polymer can be fabricated into Glutathione (GSH) responsive nanoparticles which can be used as an intracellular drug delivery system. Different from common Poly(lactide-co-glycolide) (PLGA) polymer, the lactic and glycolic units in Poly(lactide-alt-glycolide) block alternate in sequence in the polymer chain, and the molar ratio of lactic to glycolic units in the polymer is exactly 1:1.Poly(lactide-alt-glycolide) exhibits excellent solubility in common organic solvents, such as acetonitrile, acetone, dioxane, DCM, and THF, providing great convenience for drug delivery researches and applications.

SAFETY INFORMATION

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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