P4413
N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine
≥98% (TLC), powder, membrane-permeable zinc chelator
Manufacturer: Sigma Aldrich
CAS Number: 16858-02-9
Synonym(S): TPEN
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | P4413-50-MG | In Stock | ₹ 11,799.25 |
| 100 MG | P4413-100-MG | In Stock | ₹ 19,647.38 |
P4413 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 11,799.25
GST (18%): ₹ 2,123.865
Total Price: ₹ 13,923.115
product name
N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine,
form
powder
Quality Level
100
SMILES string
C(CN(Cc1ccccn1)Cc2ccccn2)N(Cc3ccccn3)Cc4ccccn4
InChI
1S/C26H28N6/c1-5-13-27-23(9-1)19-31(20-24-10-2-6-14-28-24)17-18-32(21-25-11-3-7-15-29-25)22-26-12-4-8-16-30-26/h1-16H,17-22H2
InChI key
CVRXLMUYFMERMJ-UHFFFAOYSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | MilliporeSigma™ Calbiochem™ TPEN | MilliporeSigma™ | ₹ 18,617.00 | |
 | Sigma Aldrich Fine Chemicals Biosciences N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine | 16858-02-9 | MFCD00036918 | 50MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 10,795.96 | |
 | eMolecules Ambeed / N1N1N2N2-Tetrakis(pyridin-2-ylmethyl)ethane-12-diamine / 1mg / 761012698 / A539105 / / 16858-02-9 / MFCD00036918 / 424.552 / C26H28N6 | eMolecules | ₹ 2,065.42 | |
| | Cayman Chemical TPEN, 16858-02-9, 10 mg | Cayman Chemical | ₹ 2,703.70 | |
 | TPEN | Millipore | ₹ 18,010.00 | |
 | 1,2-Ethanediamine, N,N,N',N'-tetrakis(2-pyridinylmethyl)- | Aaron Chemicals LLC | ₹ 855.60 - ₹ 5,390.28 | |
 | TPEN | ChemScene | ₹ 5,732.52 - ₹ 6,588.12 |
Related Products
Description
- Application: N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine has been used:in the treatment of human embryonic kidney (HEK293T) cells for assessing its effect on the Jembrana disease virus (JDV) viral infectivity factor (Vif) functionality[1]in P19 embryonic carcinoma cells for chelation of zinc ions released during apoptosis[2] to evaluate its effect on lentiviral Vpx infection on human monocytic THP-1 cells[3]
- Biochem/physiol Actions: N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine (TPEN) elicits pro-apoptotic effect in human acute promyelocytic NB4 cells by inhibiting nitric oxide signalling and Zn2+ signaling.[4] In microglia pretreated with zinc, TPEN inhibits the interleukin 6 secretion and nitric oxide synthase (iNOS) mRNA expression.[5] It induces damage on DNA structure by activating ATM (ataxia telangiectasia mutated) and ATR (ATM-Rad3-related) signaling in human colon cancer cells.[6]
- Features and Benefits: This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
SAFETY INFORMATION
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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product name: N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine,
form: powder
Quality Level: 100
SMILES string: C(CN(Cc1ccccn1)Cc2ccccn2)N(Cc3ccccn3)Cc4ccccn4
InChI: 1S/C26H28N6/c1-5-13-27-23(9-1)19-31(20-24-10-2-6-14-28-24)17-18-32(21-25-11-3-7-15-29-25)22-26-12-4-8-16-30-26/h1-16H,17-22H2
InChI key: CVRXLMUYFMERMJ-UHFFFAOYSA-N
product name:
N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine,
form:
powder
Quality Level:
100
SMILES string:
C(CN(Cc1ccccn1)Cc2ccccn2)N(Cc3ccccn3)Cc4ccccn4
InChI:
1S/C26H28N6/c1-5-13-27-23(9-1)19-31(20-24-10-2-6-14-28-24)17-18-32(21-25-11-3-7-15-29-25)22-26-12-4-8-16-30-26/h1-16H,17-22H2
InChI key:
CVRXLMUYFMERMJ-UHFFFAOYSA-N
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