09-231-0R

Tocris Bioscience™ SR 141716A

Manufacturer: Tocris Bioscience™

CAS Number: 158681-13-1

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Chemical Name or Material

N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride

Assay Percent Range

>99%

Solubility

Soluble to 100mM in DMSO

Formula Weight

Observed MW: 500.25

CAS

158681-13-1

Quantity

10 mg

Molecular Formula

C22H21Cl3N4O.HCl

Other Options

Image Product Name Manufacturer Price Range
AA81109
158681-13-1 | 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide hydrochloride
A2B Chem ₹ 2,053.44 - ₹ 12,149.52

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Description

  • SR 141716A is a potent and selective cannabinoid CB1 receptor antagonist (Ki = 1.98 nM)
  • Also acts as an inverse agonist reversing adenylyl cyclase inhibition by WIN 55,212-2 (Cat.No
  • 1038) (IC50 = 48 nM)
  • Displays no activity at CB2 receptors
  • Reduces food intake and body weight in orally dosed non-obese Wistar rats
  • Also μ-opioid receptor antagonist (Ki = 652 nm)

SAFETY INFORMATION

  • Recommended Storage : Desiccate at Room Temperature

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Tocris Bioscience™

09-231-0R

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Chemical Name or Material:
N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide hydrochloride

Assay Percent Range:
>99%

Solubility:
Soluble to 100mM in DMSO

Formula Weight:
Observed MW: 500.25

CAS:
158681-13-1

Quantity:
10 mg

Molecular Formula:
C22H21Cl3N4O.HCl

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09-241-MI

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Formula Weight:
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CAS:
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Quantity:
100 μg

Molecular Formula:
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Fischer Scientific

09-263-3020

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Assay Percent Range:
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Solubility:
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Formula Weight:
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CAS:
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Quantity:
10 x 1 L

Molecular Formula:
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Sigma Aldrich

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