200007286
Tocris Bioscience™ XIE62-1004
Inducer of autophagy via interaction of p62 and LC3
Manufacturer: Fischer Scientific
CAS Number: 2421146-32-7
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Chemical Name or Material
2-[[[3,4-Bis(phenylmethoxy)phenyl]methyl]amino]ethanol hydrochloride
Target
p62/SQSTM1
Purity
0.98
CAS
2421146-32-7
Molecular Formula
C23H25NO3.HCl
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ XIE62-1004 | Fischer Scientific | ₹ 64,864.75 | |
| | Tocris Bioscience™ XIE62-1004 | Fischer Scientific | ₹ 15,491.49 | |
 | 2421146-32-7 | 2-((3,4-BIS(BENZYLOXY)BENZYL)AMINO)ETHAN-1-OL HYDROCHLORIDE | A2B Chem | ₹ 2,310.12 - ₹ 25,154.64 |
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Description
- XIE62-1004 is an inducer of p62-LC3 interaction
- Binds to the ZZ domain of p62, leading to p62 self-aggregation and interaction with LC3 on autophagosome membranes; facilitates delivery of cargo proteins to the autophagosome for degradation
- Active in vitro and in vivo in a concentration- and time-dependent manner and is specific for wild type p62
- Induces degradation of mutant huntingtin in vitro
- Can also be used in AUTAC protein degradation systems to induce autophagy through p62 self-aggregation and LC3 interaction.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
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Chemical Name or Material: 2-[[[3,4-Bis(phenylmethoxy)phenyl]methyl]amino]ethanol hydrochloride
Target: p62/SQSTM1
Purity: 0.98
CAS: 2421146-32-7
Molecular Formula: C23H25NO3.HCl
Chemical Name or Material:
2-[[[3,4-Bis(phenylmethoxy)phenyl]methyl]amino]ethanol hydrochloride
Target:
p62/SQSTM1
Purity:
0.98
CAS:
2421146-32-7
Molecular Formula:
C23H25NO3.HCl
Chemical Name or Material: 3-[1-(6,7-Dichloro-1 H-benzimidazol-2-yl)-5-hydroxy-3-methyl-1 H-pyrazol-4-yl]-1(3 H)-isobenzofuranone
Target: Synthase/Synthetase Inhibitors
Purity: 0.98
CAS: 2262452-06-0
Molecular Formula: C19H12Cl2N4O3
Chemical Name or Material:
3-[1-(6,7-Dichloro-1 H-benzimidazol-2-yl)-5-hydroxy-3-methyl-1 H-pyrazol-4-yl]-1(3 H)-isobenzofuranone
Target:
Synthase/Synthetase Inhibitors
Purity:
0.98
CAS:
2262452-06-0
Molecular Formula:
C19H12Cl2N4O3
Chemical Name or Material: 2-Ethyl-4,5,6,7-tetrahydro-N-[2-[(tetrahydro-2 H-pyran-2-yl)methoxy]phenyl]-2 H-indazole-3-carboxamide
Target: IP3R1
Purity: 0.98
CAS: 1214569-31-9
Molecular Formula: C22H29N3O3
Chemical Name or Material:
2-Ethyl-4,5,6,7-tetrahydro-N-[2-[(tetrahydro-2 H-pyran-2-yl)methoxy]phenyl]-2 H-indazole-3-carboxamide
Target:
IP3R1
Purity:
0.98
CAS:
1214569-31-9
Molecular Formula:
C22H29N3O3
Chemical Name or Material: 4-[3-(2-Cyclohexylethoxy)benzoyl]-N-phenyl-1-piperazinecarboxamide
Target: YAP1
Purity: 0.98
CAS: 1008768-41-9
Molecular Formula: C26H33N3O3
Chemical Name or Material:
4-[3-(2-Cyclohexylethoxy)benzoyl]-N-phenyl-1-piperazinecarboxamide
Target:
YAP1
Purity:
0.98
CAS:
1008768-41-9
Molecular Formula:
C26H33N3O3