42-655-0
Tocris Bioscience™ AS 1842856
Manufacturer: Fischer Scientific
CAS Number: 836620-48-5
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 42-655-0-Each-of-1 | In Stock | ₹ 52,065.00 |
42-655-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,065.00
GST (18%): ₹ 9,371.70
Total Price: ₹ 61,436.70
Chemical Name or Material
5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
Quantity
50 mg
Purity
98%
CAS
836620-48-5
Molecular Formula
C18H22FN3O3
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ AS 1842856 | -- | -- | ||
Tocris Bioscience™ AS 1842856 | -- | ₹ 12,727.00 | ||
Medchemexpress LLC HY-100596 10mg , AS1842856 CAS:836620-48-5 Purity:>98% | -- | ₹ 7,849.80 | ||
Selleck Chemical LLC AS1842856 10mg 836620-48-5 | -- | ₹ 15,699.60 | ||
836620-48-5 | As1842856 | -- | ₹ 2,492.00 - ₹ 5,53,313.00 |
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Description
- Potent and selective Foxo1 inhibitor (IC50 values are 33 nM at Foxo1 and >1 μM at Foxo3a and Foxo4); decreases Foxo-mediated promoter activity by 70%, 20% and 3% at Foxo1, Foxo4 and Foxo3, respectively
- Regulates gluconeogenesis both in vitro and in vivo
- Attenuates fasting plasma glucose level in diabetic db/db mice
- Also suppresses autophagy, adipocyte differentiation and soluble guanylyl cyclase expression
- Also inhibits STAT3 signaling in NSCLC
- Orally bioavailable.