533950

Tocris Bioscience™ PFK 15

Manufacturer: Fischer Scientific

CAS Number: 4382-63-2

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Pack Size SKU Availability Price
Each of 1 533950-Each-of-1 In Stock ₹ 76,405.08

533950 - Each of 1

₹ 76,405.08

In Stock

Quantity

1

Base Price: ₹ 76,405.08

GST (18%): ₹ 13,752.914

Total Price: ₹ 90,157.994

Chemical Name or Material

PFK 15

Synonym

1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one

Solubility

Soluble to 100mM in DMSO

Formula Weight

260.29

Product Type

Bioactive Small Molecule

CAS

4382-63-2

Quantity

50 mg

Molecular Formula

C17H12N2O

Physical Form

Solid

Purity

>99%

Other Options

Image Product Name Manufacturer Price Range
7082182
Tocris Bioscience™ PFK 15
Fischer Scientific --
533910
Tocris Bioscience™ PFK 15
Fischer Scientific ₹ 18,267.06
50-186-6755
Sigma Aldrich Fine Chemicals Biosciences PFK15 >=98% (HPLC) | 4382-63-2 | 25MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 50,206.61

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Description

  • Description Originally reported to be a selective PFKFB3 inhibitor (IC50 = 207 nM); a more recent report failed to demonstrate activity in a PFKFB3 kinase assay
  • Selective for PFKFB3 over a panel of 96 kinases
  • Reduces glucose uptake and induces apoptosis in H522 lung adenocarcinoma and Jurkat T cell leukemia cells
  • Suppresses glucose uptake and tumor growth, and inhibits metastasis of Lewis lung carcinoma cell xenografts in mice.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Fischer Scientific

533950

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Chemical Name or Material:
PFK 15

Synonym:
1-(4-Pyridinyl)-3-(2-quinolinyl)-2-propen-1-one

Solubility:
Soluble to 100mM in DMSO

Formula Weight:
260.29

Product Type:
Bioactive Small Molecule

CAS:
4382-63-2

Quantity:
50 mg

Molecular Formula:
C17H12N2O

Physical Form:
Solid

Purity:
>99%

Img

Sigma Aldrich

533955

50-100 mesh, extent of labeling: 0....


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Supelco

53396

TraceCERT®, certified reference mat...


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Sigma Aldrich

533963

average Mn ~2,000...


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