57-905-0

Tocris Bioscience™ PF 05175157

Manufacturer: Fischer Scientific

CAS Number: 1301214-47-0

Select a Size

Pack Size SKU Availability Price
Each of 1 57-905-0-Each-of-1 In Stock ₹ 94,073.00

57-905-0 - Each of 1

₹ 94,073.00

In Stock

Quantity

1

Base Price: ₹ 94,073.00

GST (18%): ₹ 16,933.14

Total Price: ₹ 1,11,006.14

Chemical Name or Material

1,4-Dihydro-1′-[2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4′-piperidin]-7(6H)-one

Quantity

50 mg

Molecular Formula

C23H27N5O2

Purity

>98%

CAS

1301214-47-0

Target

Additional Lipid Metabolism Compounds

Formula Weight

405.49

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Description

  • PF 05175157 is an potent acetyl-CoA carboxylase (ACC) 2 and 1 inhibitor (IC50 values are 45 and 98 nM, respectively)
  • Reduces hepatic and skeletal muscle malonyl-CoA levels in rats
  • Also inhibits hepatic de novo lipogenesis and reduces whole body respiratory exchange ratio in rats
  • Orally bioavailable.

SAFETY INFORMATION

  • Recommended Storage : Store at 4°C