7110909
Tocris Bioscience™ PF 05175157
Acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor
Manufacturer: Fischer Scientific
CAS Number: 1301214-47-0
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Chemical Name or Material
1,4-Dihydro-1′-[2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4′-piperidin]-7(6H)-one
Target
Additional Lipid Metabolism Compounds
Formula Weight
405.49
CAS
1301214-47-0
Molecular Formula
C23H27N5O2
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
Tocris Bioscience™ PF 05175157 | -- | ₹ 22,339.00 | ||
Tocris Bioscience™ PF 05175157 | -- | ₹ 94,073.00 | ||
Medchemexpress LLC HY-12942 50mg , PF-05175157 CAS:1301214-47-0 Purity:>98% | -- | ₹ 50,369.55 | ||
eMolecules Ambeed / 1-Isopropyl-1-(2-methyl-1H-benzo[d]imidazole-6-carbonyl)-46-dihydrospiro[indazole-54-piperidin]-7(1H)-one / 5mg / 534568827 / A724655 / / 1301214-47-0 / MFCD28502250 / 405.502 / C23H27N5O2 | -- | ₹ 9,956.43 | ||
1301214-47-0 | Spiro[5H-indazole-5,4'-piperidin]-7(6H)-one,1,4-dihydro-1'-[(2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)- | -- | ₹ 2,670.00 - ₹ 1,35,725.00 |
Related Products
Description
- PF 05175157 is an potent acetyl-CoA carboxylase (ACC) 2 and 1 inhibitor (IC50 values are 45 and 98 nM, respectively)
- Reduces hepatic and skeletal muscle malonyl-CoA levels in rats
- Also inhibits hepatic de novo lipogenesis and reduces whole body respiratory exchange ratio in rats
- Orally bioavailable.
SAFETY INFORMATION
- Recommended Storage : Store at 4°C