60-085-0
Tocris Bioscience™ TP 064
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 60-085-0-Each-of-1 | In Stock | ₹ 78,152.68 |
60-085-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 78,152.68
GST (18%): ₹ 14,067.482
Total Price: ₹ 92,220.162
Chemical Name or Material
TP 064
Quantity
50 mg
Molecular Formula
C28H34N4O2
Physical Form
Solid
Product Type
Bioactive Small Molecule
Synonym
N-Methyl-N-((2-(1-(2-(methylamino)ethyl)piperidin-4-yl)pyridin-4-yl)methyl)-3-phenoxybenzamide
Solubility
Soluble to 100mM in 1eq. HCl and to 100mM in DMSO
Formula Weight
458.6
Color
White
Purity
>98%
Related Products
Description
- TP 064 is a potent and selective PRMT4 inhibitor; inhibits methylation of H3 (1-25) and MED12 (IC50 values are <10 and 43 nM, respectively)
- Exhibits >100-fold selectivity over other histone methyltransferases and non-epigenetic targets
- Inhibits proliferation of certain multiple myeloma cell lines, arresting cells in G1 phase
- TP 064 can be used in vivo
- TP 064 inhibits the monocyte/macrophage-driven inflammation in ex vivo
- To request the negative control for TP 064, please fill out the TP 064N request form on the SGC website
- .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C