60-085-0

Tocris Bioscience™ TP 064

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 60-085-0-Each-of-1 In Stock ₹ 75,131.95

60-085-0 - Each of 1

₹ 75,131.95

In Stock

Quantity

1

Base Price: ₹ 75,131.95

GST (18%): ₹ 13,523.751

Total Price: ₹ 88,655.701

Chemical Name or Material

TP 064

Quantity

50 mg

Molecular Formula

C28H34N4O2

Physical Form

Solid

Product Type

Bioactive Small Molecule

Synonym

N-Methyl-N-((2-(1-(2-(methylamino)ethyl)piperidin-4-yl)pyridin-4-yl)methyl)-3-phenoxybenzamide

Solubility

Soluble to 100mM in 1eq. HCl and to 100mM in DMSO

Formula Weight

458.6

Color

White

Purity

>98%

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Description

  • TP 064 is a potent and selective PRMT4 inhibitor; inhibits methylation of H3 (1-25) and MED12 (IC50 values are <10 and 43 nM, respectively)
  • Exhibits >100-fold selectivity over other histone methyltransferases and non-epigenetic targets
  • Inhibits proliferation of certain multiple myeloma cell lines, arresting cells in G1 phase
  • TP 064 can be used in vivo
  • TP 064 inhibits the monocyte/macrophage-driven inflammation in ex vivo
  • To request the negative control for TP 064, please fill out the TP 064N request form on the SGC website
  • .

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

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Fischer Scientific

60-085-0

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Chemical Name or Material:
TP 064

Quantity:
50 mg

Molecular Formula:
C28H34N4O2

Physical Form:
Solid

Product Type:
Bioactive Small Molecule

Synonym:
N-Methyl-N-((2-(1-(2-(methylamino)ethyl)piperidin-4-yl)pyridin-4-yl)methyl)-3-phenoxybenzamide

Solubility:
Soluble to 100mM in 1eq. HCl and to 100mM in DMSO

Formula Weight:
458.6

Color:
White

Purity:
>98%

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Color:
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Honeywell Chemicals

60-090-010

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4 x 4 L

Molecular Formula:
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Physical Form:
Liquid

Product Type:
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Synonym:
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