60-291-0
Tocris Bioscience™ FRAX 597
Manufacturer: Fischer Scientific
CAS Number: 1286739-19-2
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 60-291-0-Each-of-1 | In Stock | ₹ 30,260.00 |
60-291-0 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,260.00
GST (18%): ₹ 5,446.80
Total Price: ₹ 35,706.80
Chemical Name or Material
FRAX 597
Synonym
6-[2-Chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7-(8H)-one
Solubility
Soluble to 20mM in DMSO
Molecular Formula
C29H28ClN7OS
Physical Form
Solid
Product Type
Bioactive Small Molecule
CAS
1286739-19-2
Quantity
10 mg
Target
PAK Inhibitors
Formula Weight
558.1
Color
Yellow
Purity
>98%
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Tocris Bioscience™ FRAX 597 | Fischer Scientific | -- | |
| | Tocris Bioscience™ FRAX 597 | Fischer Scientific | ₹ 1,26,736.00 | |
 | Selleck Chemical LLC FRAX597 5mg 1286739-19-2 | Selleck Chemical LLC | ₹ 21,039.60 | |
 | Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-[2-chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]- | Aaron Chemicals LLC | ₹ 2,047.00 - ₹ 13,528.00 |
Related Products
Description
- Potent group I PAK inhibitor (IC50 values are 8, 13 and 19 nM for PAK1, 2 and 3, respectively)
- Exhibits significant inhibition of YES1, RET, CSF1R and TEK at 100 nM, but is inactive against group II PAK isoforms (IC50 >10 μM for PAK4)
- Inhibits proliferation of pancreatic cancer and schwannoma cells in vitro and exhibits antitumor effects in mice.
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: FRAX 597
Synonym: 6-[2-Chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7-(8H)-one
Solubility: Soluble to 20mM in DMSO
Molecular Formula: C29H28ClN7OS
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 1286739-19-2
Quantity: 10 mg
Target: PAK Inhibitors
Formula Weight: 558.1
Color: Yellow
Purity: >98%
Chemical Name or Material:
FRAX 597
Synonym:
6-[2-Chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7-(8H)-one
Solubility:
Soluble to 20mM in DMSO
Molecular Formula:
C29H28ClN7OS
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
1286739-19-2
Quantity:
10 mg
Target:
PAK Inhibitors
Formula Weight:
558.1
Color:
Yellow
Purity:
>98%
Chemical Name or Material: FRAX 597
Synonym: 6-[2-Chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7-(8H)-one
Solubility: Soluble to 20mM in DMSO
Molecular Formula: C29H28ClN7OS
Physical Form: Solid
Product Type: Bioactive Small Molecule
CAS: 1286739-19-2
Quantity: 50 mg
Target: PAK Inhibitors
Formula Weight: 558.1
Color: Yellow
Purity: >98%
Chemical Name or Material:
FRAX 597
Synonym:
6-[2-Chloro-4-(5-thiazolyl)phenyl]-8-ethyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7-(8H)-one
Solubility:
Soluble to 20mM in DMSO
Molecular Formula:
C29H28ClN7OS
Physical Form:
Solid
Product Type:
Bioactive Small Molecule
CAS:
1286739-19-2
Quantity:
50 mg
Target:
PAK Inhibitors
Formula Weight:
558.1
Color:
Yellow
Purity:
>98%
Chemical Name or Material: __
Synonym: __
Solubility: __
Molecular Formula: __
Physical Form: __
Product Type: Peptide
CAS: 21215-62-3
Quantity: 500 μg
Target: __
Formula Weight: __
Color: __
Purity: 0.95
Chemical Name or Material:
__
Synonym:
__
Solubility:
__
Molecular Formula:
__
Physical Form:
__
Product Type:
Peptide
CAS:
21215-62-3
Quantity:
500 μg
Target:
__
Formula Weight:
__
Color:
__
Purity:
0.95
Chemical Name or Material: __
Synonym: __
Solubility: __
Molecular Formula: __
Physical Form: __
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CAS: 1211877-36-9
Quantity: 10mg
Target: __
Formula Weight: __
Color: __
Purity: __
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Synonym:
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Solubility:
__
Molecular Formula:
__
Physical Form:
__
Product Type:
N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-D-leucinamide
CAS:
1211877-36-9
Quantity:
10mg
Target:
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Formula Weight:
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