60-385-0

Tocris Bioscience™ SR 10067

Manufacturer: Fischer Scientific

CAS Number: 1380548-02-6

Select a Size

Pack Size SKU Availability Price
Each of 1 60-385-0-Each-of-1 In Stock ₹ 84,656.80

60-385-0 - Each of 1

₹ 84,656.80

In Stock

Quantity

1

Base Price: ₹ 84,656.80

GST (18%): ₹ 15,238.224

Total Price: ₹ 99,895.024

Chemical Name or Material

[3-[[4-(1,1-Dimethylethoxy)phenoxy]methyl]-3,4-dihydro-2(1H)-isoquinolinyl]-1-naphthalenylmethanone

Assay Percent Range

>98%

Molecular Formula

C31H31NO3

CAS

1380548-02-6

Quantity

50 mg

Formula Weight

Observed MW: 465.58

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Description

  • Selective Rev-Erbα/β agonist (IC50 values are 160 and 170 nM for Rev-Erbβ and Rev-Erbα respectively)
  • Exhibits no significant activity against a wide range of nuclear receptors, other receptors, ion channels and transporters at 20 μM
  • Increases wakefulness, reduces REM and slow wave sleep in vivo
  • Also reduces anxiety-like behavior in marble-burying assay
  • Cell permeable and brain penetrant.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C