62-725

Tocris Bioscience™ KYP 2047

Manufacturer: Fischer Scientific

CAS Number: 796874-99-2

Select a Size

Pack Size SKU Availability Price
Each of 1 62-725-Each-of-1 In Stock ₹ 16,444.63

62-725 - Each of 1

₹ 16,444.63

In Stock

Quantity

1

Base Price: ₹ 16,444.63

GST (18%): ₹ 2,960.033

Total Price: ₹ 19,404.663

Chemical Name or Material

(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile

Quantity

5 mg

Formula Weight

339.44

CAS

796874-99-2

Molecular Formula

C20H25N3O2

Purity

98%

Other Options

Image Product Name Manufacturer Price Range
7161643
Tocris Bioscience™ KYP 2047
Fischer Scientific --
62-722-5
Tocris Bioscience™ KYP 2047
Fischer Scientific ₹ 63,870.54
50-173-8746
Sigma Aldrich Fine Chemicals Biosciences KYP-2047 >=95% (HPLC) | 796874-99-2 | MFCD22201003 | 25MG
Sigma Aldrich Fine Chemicals Biosciences ₹ 74,710.99
BA57510
796874-99-2 | KYP-2047;796874-99-2
A2B Chem ₹ 4,620.24 - ₹ 45,432.36

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Description

  • KYP 2047 is a high affinity prolyl oligopeptidase (POP) inhibitor (Ki = 0.023 nM)
  • Clears α-synuclein aggregates induced by oxidative stress in neuronal cells
  • Inhibits the formation of AcSDKP from its precursor 43-mer thymosin β4 (Tβ4)
  • Induces angiogenesis via POP inhibition
  • It reduces tau aggregation in tau-transfected HEK-293 cells and N2A cells as well as in human iPSC-derived neurons from patients with frontotemporal dementia
  • In vivo , treatment with KYP 2047 of transgenic mice with tauopathy, reduces tau aggregation in the brain and cerebrospinal fluid and slows cognitive decline
  • Anti-angiogenic and neuroprotective
  • Brain penetrant.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

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Fischer Scientific

62-725

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Chemical Name or Material:
(2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile

Quantity:
5 mg

Formula Weight:
339.44

CAS:
796874-99-2

Molecular Formula:
C20H25N3O2

Purity:
98%

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Tocris Bioscience™

62-731-0

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Chemical Name or Material:
4-[[5-[3-(2-Chloro-4-methylphenyl)-4-pyridinyl]-2-thiazolyl]amino]phenol

Quantity:
10 mg

Formula Weight:
__

CAS:
1661845-86-8

Molecular Formula:
C21H16ClN3OS

Purity:
98%

Img

MilliporeSigma™

62-760-91MG

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Chemical Name or Material:
__

Quantity:
1 mg

Formula Weight:
467.5g/mol

CAS:
__

Molecular Formula:
__

Purity:
__

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Fischer Scientific

62-782-5

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Chemical Name or Material:
5-[2-Chloro-6-(trifluoromethoxy)phenyl]-1,3-dihydro-2H-benzimidazol-2-one

Quantity:
25 mg

Formula Weight:
Observed MW: 328.67

CAS:
2036081-86-2

Molecular Formula:
C14H8ClF3N2O2

Purity:
__