64-165

CM 11

Manufacturer: R&D Systems

CAS Number: 2244684-49-7

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Pack Size SKU Availability Price
Each of 1 64-165-Each-of-1 In Stock ₹ 45,603.48

64-165 - Each of 1

₹ 45,603.48

In Stock

Quantity

1

Base Price: ₹ 45,603.48

GST (18%): ₹ 8,208.626

Total Price: ₹ 53,812.106

CAS

2244684-49-7

Quantity

5 mg

Formula Weight

1179.46

Synonym

N1,N20-bis((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-3,6,9,12,15,18-hexaoxaicosanediamide

Molecular Formula

C58H82N8O14S2

Purity

98%

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Description

  • CM 11 is a PROTAC® for self-degradation of the long form of VHL, pVHL30 (DC50 < 100 nM)
  • Composed of two VHL ligands joined by a linker
  • Exhibits > 1000-fold increased cellular activity compared to the parent VHL ligand, VH 032
  • Dimerizes pVHL30 with high avidity in vitro
  • Induced potent and rapid self-degradation of VHL in cell lines in a highly isoform dependent fashion
  • Negative control CMP 98 (Cat
  • No
  • 6417) also available
  • PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

Img

R&D Systems

64-165

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CAS:
2244684-49-7

Quantity:
5 mg

Formula Weight:
1179.46

Synonym:
N1,N20-bis((S)-1-((2S,4R)-4-Hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-3,6,9,12,15,18-hexaoxaicosanediamide

Molecular Formula:
C58H82N8O14S2

Purity:
98%

Img

Fischer Scientific

64-166-841

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CAS:
__

Quantity:
25 Tests

Formula Weight:
__

Synonym:
__

Molecular Formula:
__

Purity:
__

Img

Fischer Scientific

64-166-842

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CAS:
__

Quantity:
100 Tests

Formula Weight:
__

Synonym:
__

Molecular Formula:
__

Purity:
__

Img

R&D Systems

64-192

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CAS:
__

Quantity:
2 mg

Formula Weight:
Observed MW: 629.69

Synonym:
__

Molecular Formula:
C33H29F2N3O6Si

Purity:
__