72-665
Tocris™ SJF 8240
Manufacturer: Tocris™
CAS Number: 2230821-68-6
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 72-665-Each-of-1 | In Stock | ₹ 30,502.14 |
72-665 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 30,502.14
GST (18%): ₹ 5,490.385
Total Price: ₹ 35,992.525
Chemical Name or Material
N-(3-Fluoro-4-((7-(3-(3-(3-((-1-((2 S,4 R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-3-oxopropoxy)propoxy)propoxy)-6-methoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dic
Quantity
5 mg
Molecular Formula
C58H65F2N7O11S
CAS
2230821-68-6
Target
Active Degraders
Purity
0.98
Related Products
Description
- SJF 8240 is a c-MET PROTAC™Degrader
- Comprises MET inhibitor foretinib (GSK 1363089; Cat
- No
- 6056) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand
- Degrades c-MET within 6 hours in vitro
- Inhibits agonist-driven AKT phosphorylation and GTL16 cell proliferation (IC50 = 66.7 nM)
- Also degrades exon-14-deleted c-MET in Hs746T cells
- PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
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Chemical Name or Material: N-(3-Fluoro-4-((7-(3-(3-(3-((-1-((2 S,4 R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-3-oxopropoxy)propoxy)propoxy)-6-methoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dic
Quantity: 5 mg
Molecular Formula: C58H65F2N7O11S
CAS: 2230821-68-6
Target: Active Degraders
Purity: 0.98
Chemical Name or Material:
N-(3-Fluoro-4-((7-(3-(3-(3-((-1-((2 S,4 R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-3-oxopropoxy)propoxy)propoxy)-6-methoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dic
Quantity:
5 mg
Molecular Formula:
C58H65F2N7O11S
CAS:
2230821-68-6
Target:
Active Degraders
Purity:
0.98
Chemical Name or Material: N-(3-Fluoro-4-((7-(4-(4-(2-((-1-((2 S,4 R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)butoxy)butoxy)-6-methoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarb
Quantity: 5 mg
Molecular Formula: C59H67F2N7O11S
CAS: 2254609-27-1
Target: Active Degraders
Purity: 0.98
Chemical Name or Material:
N-(3-Fluoro-4-((7-(4-(4-(2-((-1-((2 S,4 R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)butoxy)butoxy)-6-methoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarb
Quantity:
5 mg
Molecular Formula:
C59H67F2N7O11S
CAS:
2254609-27-1
Target:
Active Degraders
Purity:
0.98
Chemical Name or Material: 2-[3 '-Fluoro-5 '-[1-[2-(methylamino)-2-oxoethyl]-1 H-pyrazol-4-yl]-2,5-dioxo-2 ',3 '-dihydrospiro(imidazolidine-4,1 '-inden)-1-yl]-N-(4-fluorobenzyl)-N-(1,1,1-trifluoropropane-2-yl)acetamide
Quantity: 5 mg
Molecular Formula: C29H27F5N6O4
CAS: __
Target: Histone Acetyltransferase Inhibitors
Purity: 0.98
Chemical Name or Material:
2-[3 '-Fluoro-5 '-[1-[2-(methylamino)-2-oxoethyl]-1 H-pyrazol-4-yl]-2,5-dioxo-2 ',3 '-dihydrospiro(imidazolidine-4,1 '-inden)-1-yl]-N-(4-fluorobenzyl)-N-(1,1,1-trifluoropropane-2-yl)acetamide
Quantity:
5 mg
Molecular Formula:
C29H27F5N6O4
CAS:
__
Target:
Histone Acetyltransferase Inhibitors
Purity:
0.98
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