72-685

Tocris™ SJFa SJFalpha SJFalpha

Manufacturer: Tocris™

CAS Number: 2254609-27-1

Select a Size

Pack Size SKU Availability Price
Each of 1 72-685-Each-of-1 In Stock ₹ 30,502.14

72-685 - Each of 1

₹ 30,502.14

In Stock

Quantity

1

Base Price: ₹ 30,502.14

GST (18%): ₹ 5,490.385

Total Price: ₹ 35,992.525

Chemical Name or Material

N-(3-Fluoro-4-((7-(4-(4-(2-((-1-((2 S,4 R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)butoxy)butoxy)-6-methoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarb

Quantity

5 mg

Molecular Formula

C59H67F2N7O11S

CAS

2254609-27-1

Target

Active Degraders

Purity

0.98

Other Options

Image Product Name Manufacturer Price Range
50-249-8674
eMolecules​ Medchem Express / SJF / 5mg / 721434917 / HY-114404 / / 2254609-27-1 / [null] / 1120.280 / C59H67F2N7O11S
eMolecules​ ₹ 32,745.52

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Description

  • SJFα is a potent and selective p38α PROTAC™ Degrader (DC50 = 7.16 nM and Dmax = 97.4%)
  • SJFα comprises the multikinase inhibitor foretinib joined by a linker to a VHL ligand
  • Displays significantly lower potency degradation at p38δ (DC50 = 299 nM)
  • Exhibits no significant degradation of p38β or γ
  • or related MAPKs, ERK1/2, or JNK1/2
  • PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license .

SAFETY INFORMATION

  • Recommended Storage : Store at -20°C

Compare Similar Items

Show Difference

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Tocris™

72-685

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Chemical Name or Material:
N-(3-Fluoro-4-((7-(4-(4-(2-((-1-((2 S,4 R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-2-oxoethoxy)butoxy)butoxy)-6-methoxyquinolin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarb

Quantity:
5 mg

Molecular Formula:
C59H67F2N7O11S

CAS:
2254609-27-1

Target:
Active Degraders

Purity:
0.98

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Chemical Name or Material:
2-[3 '-Fluoro-5 '-[1-[2-(methylamino)-2-oxoethyl]-1 H-pyrazol-4-yl]-2,5-dioxo-2 ',3 '-dihydrospiro(imidazolidine-4,1 '-inden)-1-yl]-N-(4-fluorobenzyl)-N-(1,1,1-trifluoropropane-2-yl)acetamide

Quantity:
5 mg

Molecular Formula:
C29H27F5N6O4

CAS:
__

Target:
Histone Acetyltransferase Inhibitors

Purity:
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LIFE TECHNOLOGIES

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Chemical Name or Material:
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Quantity:
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Molecular Formula:
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CAS:
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Target:
Fluorescent Lipids Probes and Cell Membrane Stains

Purity:
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