69-485
Tocris™ CRBN-6-5-5-VHL
Manufacturer: Tocris™
CAS Number: 2362575-45-7
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 69-485-Each-of-1 | In Stock | ₹ 44,320.08 |
69-485 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,320.08
GST (18%): ₹ 7,977.614
Total Price: ₹ 52,297.694
Chemical Name or Material
(2 S,4 R)-1-((2 S)-2-(5-((5-((6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexyl)oxy)pentyl)oxy)pentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Quantity
5 mg
Target
Active Degraders
Formula Weight
972.21
Color
Yellow
Purity
96%
CAS
2362575-45-7
Solubility
Soluble to 100mM in DMSO
Molecular Formula
C51H69N7O10S
Physical Form
Solid
Product Type
Degrader
Related Products
Description
- Potent and selective cereblon Degrader (PROTAC™) (DC50 = 1.5 nM)
- Induces complete degradation of cereblon in MM1S cells
- Comprises a cereblon E3 ligase ligand joined by a linker to a ligand for the E3 ligase VHL
- Cell-permeable
- PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license .
SAFETY INFORMATION
- Recommended Storage : Store at -20°C
Compare Similar Items
Show Difference
Chemical Name or Material: (2 S,4 R)-1-((2 S)-2-(5-((5-((6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexyl)oxy)pentyl)oxy)pentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Quantity: 5 mg
Target: Active Degraders
Formula Weight: 972.21
Color: Yellow
Purity: 96%
CAS: 2362575-45-7
Solubility: Soluble to 100mM in DMSO
Molecular Formula: C51H69N7O10S
Physical Form: Solid
Product Type: Degrader
Chemical Name or Material:
(2 S,4 R)-1-((2 S)-2-(5-((5-((6-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)hexyl)oxy)pentyl)oxy)pentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Quantity:
5 mg
Target:
Active Degraders
Formula Weight:
972.21
Color:
Yellow
Purity:
96%
CAS:
2362575-45-7
Solubility:
Soluble to 100mM in DMSO
Molecular Formula:
C51H69N7O10S
Physical Form:
Solid
Product Type:
Degrader
Chemical Name or Material: N-(2-Aminoethyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide hydrochloride
Quantity: 25 mg
Target: __
Formula Weight: 410.81
Color: __
Purity: 95%
CAS: 2341841-02-7
Solubility: __
Molecular Formula: C17H18N4O6.HCl
Physical Form: __
Product Type: Ligand
Chemical Name or Material:
N-(2-Aminoethyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide hydrochloride
Quantity:
25 mg
Target:
__
Formula Weight:
410.81
Color:
__
Purity:
95%
CAS:
2341841-02-7
Solubility:
__
Molecular Formula:
C17H18N4O6.HCl
Physical Form:
__
Product Type:
Ligand
Chemical Name or Material: 4-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]-2-(2,6-dioxo-3-piperidinyl)-1 H-isoindole-1,3(2 H)-dione hydrochloride
Quantity: 25 mg
Target: Degrader Building Blocks
Formula Weight: __
Color: __
Purity: 95%
CAS: 2387510-82-7
Solubility: __
Molecular Formula: C21N27N3O8.HCl
Physical Form: __
Product Type: __
Chemical Name or Material:
4-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]-2-(2,6-dioxo-3-piperidinyl)-1 H-isoindole-1,3(2 H)-dione hydrochloride
Quantity:
25 mg
Target:
Degrader Building Blocks
Formula Weight:
__
Color:
__
Purity:
95%
CAS:
2387510-82-7
Solubility:
__
Molecular Formula:
C21N27N3O8.HCl
Physical Form:
__
Product Type:
__
Chemical Name or Material: 4-((17-Amino-3,6,9,12,15-pentaoxaheptadecyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
Quantity: 25 mg
Target: __
Formula Weight: 574.02
Color: __
Purity: 95%
CAS: 2341841-01-6
Solubility: __
Molecular Formula: C25H35N3O10.HCl
Physical Form: __
Product Type: Ligand
Chemical Name or Material:
4-((17-Amino-3,6,9,12,15-pentaoxaheptadecyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
Quantity:
25 mg
Target:
__
Formula Weight:
574.02
Color:
__
Purity:
95%
CAS:
2341841-01-6
Solubility:
__
Molecular Formula:
C25H35N3O10.HCl
Physical Form:
__
Product Type:
Ligand